Gut check: could your microbiome influence chronic pain?

NCT ID NCT03612193

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether the bacteria in your gut are linked to the severity and recovery of Complex Regional Pain Syndrome (CRPS), a chronic pain condition. Researchers will compare gut microbiome samples from people with CRPS and their household members. They also aim to predict which newly diagnosed patients are more likely to recover. This is an observational study, meaning no treatment is given—just observation and analysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could point toward new ways to predict recovery or develop treatments for Complex Regional Pain Syndrome by targeting the gut microbiome.

What could go wrong

This is an early observational study, not a treatment trial. It may find no clear link between gut bacteria and CRPS, or results may not lead to practical therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact