Gut check: could your microbiome influence chronic pain?

NCT ID NCT03612193

Recruiting now Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether the bacteria in your gut are linked to the severity and recovery of Complex Regional Pain Syndrome (CRPS), a chronic pain condition. Researchers will compare gut microbiome samples from people with CRPS and their household members. They also aim to predict which newly diagnosed patients are more likely to recover. This is an observational study, meaning no treatment is given—just observation and analysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could point toward new ways to predict recovery or develop treatments for Complex Regional Pain Syndrome by targeting the gut microbiome.
What could go wrong: This is an early observational study, not a treatment trial. It may find no clear link between gut bacteria and CRPS, or results may not lead to practical therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMPLEX REGIONAL PAIN SYNDROMES

Contacts and locations

Locations

Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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