Gut bacteria may boost lung cancer therapy

NCT ID NCT04105270

Recruiting now Disease control Sponsor: Masonic Cancer Center, University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether taking special gut bacteria capsules (RMT) alongside standard chemotherapy and immunotherapy can help control advanced lung cancer. About 82 people with untreated non-small cell lung cancer will receive either RMT or a placebo. The goal is to see if the bacteria improve how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Restorative Microbiota Therapy (RMT) capsules
What this could lead to: If it works, this could point toward a new way to boost the immune system's response to lung cancer treatment.
What could go wrong: This is an early phase 2 trial with only 82 participants, so results may not apply to everyone. Adding gut bacteria to treatment could cause unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma of Lung lung adenocarcinoma lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOCARCINOMA OF LUNG LUNG CANCER

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Dr. Amit Kulkarni
NOT_YET_RECRUITING

Phoenix, Arizona, 85338, United States
MNCCTN Essentia Health Deer River
RECRUITING

Deer River, Minnesota, 56636, United States
MNCCTN Essentia Health Duluth
RECRUITING

Duluth, Minnesota, 55805, United States
MNCCTN Essentia Health Fosston
RECRUITING

Fosston, Minnesota, 56542, United States
MNCCTN Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States
MNCCTN Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 550723, United States
MNCCTN Essentia Health St. Joseph's Brainerd Medical Center
RECRUITING

Brainerd, Minnesota, 56401, United States
MNCCTN Essentia Health St. Mary's Detroit Lakes Clinic
RECRUITING

Detroit Lakes, Minnesota, 56501, United States
MNCCTN Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States
Masonic Cancer Center, University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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