Gut bacteria may boost lung cancer therapy

NCT ID NCT04105270

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether taking special gut bacteria capsules (RMT) alongside standard chemotherapy and immunotherapy can help control advanced lung cancer. About 82 people with untreated non-small cell lung cancer will receive either RMT or a placebo. The goal is to see if the bacteria improve how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Restorative Microbiota Therapy (RMT) capsules

What this could lead to

If it works, this could point toward a new way to boost the immune system's response to lung cancer treatment.

What could go wrong

This is an early phase 2 trial with only 82 participants, so results may not apply to everyone. Adding gut bacteria to treatment could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma of Lung lung adenocarcinoma lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dr. Amit Kulkarni

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85338, United States

    Contact Phone: •••-•••-••••

  • MNCCTN Essentia Health Deer River

    RECRUITING

    Deer River, Minnesota, 56636, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health Duluth

    RECRUITING

    Duluth, Minnesota, 55805, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health Fosston

    RECRUITING

    Fosston, Minnesota, 56542, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health Hibbing Clinic

    RECRUITING

    Hibbing, Minnesota, 55746, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health Sandstone

    RECRUITING

    Sandstone, Minnesota, 550723, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health St. Joseph's Brainerd Medical Center

    RECRUITING

    Brainerd, Minnesota, 56401, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health St. Mary's Detroit Lakes Clinic

    RECRUITING

    Detroit Lakes, Minnesota, 56501, United States

    Contact Email: •••••@•••••

  • MNCCTN Essentia Health Virginia Clinic

    RECRUITING

    Virginia, Minnesota, 55792, United States

    Contact Email: •••••@•••••

  • Masonic Cancer Center, University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States