Gut bacteria could hold key to rectal cancer prognosis

NCT ID NCT04804956

Recruiting now Knowledge-focused Sponsor: University Hospital of Girona Dr. Josep Trueta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether the types of bacteria in the gut and surrounding tissues can help predict how rectal cancer will progress. Researchers will collect stool, tissue, and fat samples from 100 people with rectal cancer and compare them to healthy controls. The goal is to find microbial 'signatures' linked to better or worse survival, which could one day help tailor treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which rectal cancer patients have a worse prognosis, potentially guiding more personalized treatment decisions.
What could go wrong: This is an observational study, not a treatment trial. It is small (100 participants) and early-stage, so findings may not lead to immediate clinical changes or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER

Contacts and locations

Locations

Hospital Universitari Dr. Josep Trueta de Girona
RECRUITING

Girona, Girona, 17007, Spain

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