Head-to-Head drug battle aims to tame Crohn's Flare-Ups

NCT ID NCT07499232

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether guselkumab works better than risankizumab for people with moderate to severe Crohn's disease. About 530 adults will receive one of the two drugs and be followed for a year. The goal is to see which drug leads to deeper remission, meaning fewer symptoms and less gut inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Barts Health NHS Trust
RECRUITING

Greater London, E1 2AJ, United Kingdom
Charlotte Gastroenterology and Hepatology, PLLC
RECRUITING

Charlotte, North Carolina, 28207, United States
Clinique IMD
RECRUITING

Montreal, Quebec, H3H1E3, Canada
Clinnova Research
RECRUITING

Anaheim, California, 92805, United States
Cotton-O'Neil Clinical Research Center
RECRUITING

Topeka, Kansas, 66606, United States
Digestive Disease Specialists Inc
RECRUITING

Oklahoma City, Oklahoma, 73114, United States
Digestive Health Specialists of the Southeast
RECRUITING

Dothan, Alabama, 36305, United States
Ersta sjukhus
RECRUITING

Stockholm, 116 30, Sweden
Frontier Clinical Research
RECRUITING

Uniontown, Pennsylvania, 15401, United States
GCP Clinical Research
RECRUITING

Tampa, Florida, 33609, United States
GIRI Gastrointestinal Research Institute
RECRUITING

Vancouver, British Columbia, V6Z 2K5, Canada
Great Lakes Gastroenterology Research, LLC
RECRUITING

Mentor, Ohio, 44060, United States
Herlev Hospital
RECRUITING

Herlev, 2730, Denmark
Hoag Memorial Hospital
SUSPENDED

Newport Beach, California, 92663, United States
Karolinska Universitetssjukhuset
RECRUITING

Stockholm, 171 76, Sweden
London Digestive Disease Institute
RECRUITING

London, Ontario, N6K 1M6, Canada
London North West University Healthcare NHS Trust
RECRUITING

Greater London, NW10 7NS, United Kingdom
New York Gastroenterology Associates
RECRUITING

New York, New York, 10075, United States
Palmetto Primary and Specialty Care Physicians, Charleston
RECRUITING

Summerville, South Carolina, 29486, United States
Peak Gastroenterology Associates
RECRUITING

Colorado Springs, Colorado, 80907, United States
Sahlgrenska Universitetssjukhuset, Mölndal Sjukhus
RECRUITING

Mölndal, 431 30, Sweden
Sanchez Clinical Research, Inc
RECRUITING

Miami, Florida, 33157-6575, United States
Southern Star Research Institute, LLC
RECRUITING

San Antonio, Texas, 78229, United States
Sydvestjysk Sygehus
RECRUITING

Esbjerg, 6700, Denmark
TLC Clinical Research Inc
RECRUITING

Los Angeles, California, 90048, United States
Taunton Surgical Centre
RECRUITING

Oshawa, Ontario, L1J 0C7, Canada
The Sixth Affiliated Hospital Sun Yat sen University
RECRUITING

Guangzhou, 510655, China
Toronto Immune and Digestive Health Institute Inc
RECRUITING

Toronto, Ontario, M6A 3B4, Canada
United Gastroenterologists
RECRUITING

Los Alamitos, California, 90720, United States
Westchester Putnam Gastroenterology
RECRUITING

Carmel, New York, 10512, United States