New hope for PsA patients: which drug works best after TNFi failure?
NCT ID NCT05669833
First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 23 times
Summary
This study looks at people with psoriatic arthritis whose symptoms didn't improve enough with a TNF inhibitor. It compares switching to a different TNF inhibitor (golimumab) versus switching to a drug that blocks IL-23 (guselkumab). The goal is to see which approach better reduces joint pain, swelling, and skin symptoms. About 63 adults will take part, and the study is currently recruiting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Cincy Arthritis
RECRUITINGBlue Ash, Ohio, 45242, United States
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Cumberland Rheumatology
RECRUITINGCrossville, Tennessee, 38555, United States
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Contact Email: •••••@•••••
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Family Arthritis Center
RECRUITINGLoxahatchee Groves, Florida, 33470, United States
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Healing Rheumatology
RECRUITINGPlant City, Florida, 33563, United States
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Heritage Rheumatology and Arthritis Care
RECRUITINGColleyville, Texas, 76034, United States
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Hospital at the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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New York University
RECRUITINGNew York, New York, 10016, United States
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Parris and Associates
RECRUITINGLilburn, Georgia, 30047, United States
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Southern Ohio Rheumatology
RECRUITINGWheelersburg, Ohio, 45694, United States
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Southwest Florida Rheumatology
RECRUITINGRiverview, Florida, 33569, United States
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Texas Arthritis Center
RECRUITINGEl Paso, Texas, 79902, United States
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University of Massachusetts Chan Medical School
RECRUITINGWorcester, Massachusetts, 01655, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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