New hope for PsA patients: which drug works best after TNFi failure?

NCT ID NCT05669833

Recruiting now Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with psoriatic arthritis whose symptoms didn't improve enough with a TNF inhibitor. It compares switching to guselkumab (a different type of drug) versus switching to another TNF inhibitor called golimumab. The goal is to see which option better controls joint pain, swelling, and skin symptoms. About 63 adults will take part, and the results will help doctors choose the best next step.

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Conditions

The condition(s) this trial relates to.

psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PSORIATIC ARTHRITIS

Contacts and locations

Locations

Cincy Arthritis
RECRUITING

Blue Ash, Ohio, 45242, United States
Cumberland Rheumatology
RECRUITING

Crossville, Tennessee, 38555, United States
Family Arthritis Center
RECRUITING

Loxahatchee Groves, Florida, 33470, United States
Healing Rheumatology
RECRUITING

Plant City, Florida, 33563, United States
Heritage Rheumatology and Arthritis Care
RECRUITING

Colleyville, Texas, 76034, United States
Hospital at the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
New York University
RECRUITING

New York, New York, 10016, United States
Parris and Associates
RECRUITING

Lilburn, Georgia, 30047, United States
Southern Ohio Rheumatology
RECRUITING

Wheelersburg, Ohio, 45694, United States
Southwest Florida Rheumatology
RECRUITING

Riverview, Florida, 33569, United States
Texas Arthritis Center
RECRUITING

El Paso, Texas, 79902, United States
University of Massachusetts Chan Medical School
RECRUITING

Worcester, Massachusetts, 01655, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Utah
RECRUITING

Salt Lake City, Utah, 84132, United States

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