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Gum disease gel shows promise in early healing trial

NCT ID NCT06522438

Recruiting now Disease control Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a new gel containing hyaluronic acid and octenidine can improve gum healing after standard deep cleaning for periodontitis. About 26 adults with advanced gum disease will receive either cleaning alone or cleaning plus the gel. Researchers will measure healing markers, blood flow, and bacteria levels over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hyaluronic acid and octenidine gel
What this could lead to
If it works, this gel could help gums heal faster and better after standard treatment for periodontitis, potentially reducing the need for more invasive procedures.
What could go wrong
This is a very small, early pilot study with only 26 people. The gel is an add-on to standard care, so any benefit may be small or not seen at all. Results may not apply to everyone with gum disease.

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Conditions

The condition(s) this trial relates to.

Periodontal Attachment Loss Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL ATTACHMENT LOSS PERIODONTAL INFLAMMATION PERIODONTAL POCKET PERIODONTITIS WOUND HEAL

Contacts and locations

Locations

  • Centre for Oral Clinical Research (COCR)

    RECRUITING

    London, E1 2AD, United Kingdom

  • The Royal London Dental Hospital, Barts Health NHS Trust

    RECRUITING

    London, E1 2AD, United Kingdom

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