New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT03843359

First seen Jan 10, 2026 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This early-phase study tests a new experimental drug (GSK3745417) alone or combined with another drug (dostarlimab) in about 97 adults with advanced solid tumors that have stopped responding to standard treatments. The main goal is to find a safe dose and check for side effects. This is a first step to see if the drug might help control these cancers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • GSK Investigational Site

    Houston, Texas, 77030, United States

  • GSK Investigational Site

    Melbourne, Victoria, 3000, Australia

  • GSK Investigational Site

    Toronto, Ontario, M5G 1Z9, Canada

  • GSK Investigational Site

    Bordeaux, 33076, France

  • GSK Investigational Site

    Villejuif, 94805, France

  • GSK Investigational Site

    Tokyo, 104-0045, Japan

  • GSK Investigational Site

    Tokyo, 135-8550, Japan

  • GSK Investigational Site

    Amsterdam, 1066 CX, Netherlands

  • GSK Investigational Site

    Amsterdam, 1081 HV, Netherlands

  • GSK Investigational Site

    Seoul, 03080, South Korea

  • GSK Investigational Site

    Barcelona, 08035, Spain

  • GSK Investigational Site

    Madrid, 28040, Spain

  • GSK Investigational Site

    Madrid, 28050, Spain

Conditions

Explore the condition pages connected to this study.