Can modern Radiotherapy's late effects be predicted?

NCT ID NCT04746729

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study follows a large group of children and young adults who received radiation therapy for cancer, to see how their health and quality of life evolve over many years. By collecting medical data and blood samples in a European registry, researchers aim to identify late effects such as heart problems, hormone issues, and new cancers. The goal is to better understand the long-term risks of modern radiotherapy and improve follow-up care for future patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
This research could help doctors understand the long-term health and quality-of-life effects of modern radiotherapy in children, potentially guiding safer treatment plans for future patients.
What could go wrong
Because this is an observational registry study, it cannot prove cause and effect. Results may take many years to emerge, and the findings might not apply to all patients or treatment settings.

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Conditions

The condition(s) this trial relates to.

neoplasm Neoplasms, Radiation-Induced

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus University hospital

    RECRUITING

    Aarhus, Denmark

  • Centre Régional François Baclesse

    RECRUITING

    Caen, France

  • Gustave Roussy

    RECRUITING

    Villejuif, France

  • KU Leuven

    RECRUITING

    Leuven, Belgium

  • University Hospital Essen, The West German Proton Therapy Centre Essen

    RECRUITING

    Essen, Germany

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