New DNA test may spot kidney rejection without a needle
NCT ID NCT07060716
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a donor-derived cell-free DNA (dd-cfDNA) test can accurately detect rejection in kidney transplant recipients. Researchers will compare the test results to standard biopsy findings in 125 adults who are at least 12 days post-transplant. If the test works well, it could offer a less invasive way to monitor transplant health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
donor-derived cell-free DNA test
What this could lead to
If successful, this test could offer a simpler, less invasive way to monitor kidney transplant health and catch rejection early.
What could go wrong
This is an observational study, not a treatment trial. The test may not be accurate enough to replace biopsies, and results may vary across patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor, Scott & White Research Institute
RECRUITINGDallas, Texas, 75246, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Charite Universitatsmedizin
ACTIVE_NOT_RECRUITINGBerlin, 10117, Germany
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Institute of Immunology - Transplantation Immunology
ACTIVE_NOT_RECRUITINGHeidelberg, Baden-Wurttemberg, 69120, Germany
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Intermountain Health
RECRUITINGMurray, Utah, 84107, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Tampa General Hospital
RECRUITINGTampa, Florida, 33606, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
Contact
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University of Pittsburgh Medical Center
ACTIVE_NOT_RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Southern California Keck School of Medicine
ACTIVE_NOT_RECRUITINGLos Angeles, California, 90033, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••