Could a liver drug slow a rare brain disease?

NCT ID NCT05983588

First seen Sep 30, 2025 · Last updated May 11, 2026 · Updated 26 times

Summary

This study tests whether glycerol phenylbutyrate (GPB) can slow corticobasal syndrome (CBS), a rare and fast-progressing brain disease. About 32 adults will receive GPB or a placebo for 26 weeks. The main goal is to see if GPB lowers a marker of nerve damage in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Klinikum der Universität München (KUM), Campus Großhadern, Klinik und Poliklinik für Neurologie & German Center for Neurodegenerative Diseases (DZNE), Department of Neurology

    Munich, Bavaria, 81377, Germany

  • Klinikum rechts der Isar Technische Universität München Klinik und Poliklinik für Neurologie & German Center for Neurodegenerative Diseases (DZNE), Department of Neurology

    Munich, Bavaria, 81377, Germany

Conditions

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