50,000 iranians join quest to uncover esophageal cancer triggers

NCT ID NCT00450788

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study enrolled over 50,000 adults aged 40-75 in Iran's Golestan Province to understand why esophageal cancer is so common there. Participants filled out lifestyle and diet questionnaires and provided blood, urine, hair, and nail samples. Researchers are analyzing factors like diet, hot tea consumption, tobacco, opium, and genetics to find possible causes. No treatment or intervention was tested.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could identify key risk factors for esophageal cancer, pointing toward prevention strategies in high-risk populations.

What could go wrong

This is an observational study, not a treatment trial. It cannot prove cause and effect, and findings may not apply to other regions or groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

digestive system disorder esophageal cancer Esophageal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Digestive Disease Research Institute

    Tehran, 14117-1313, Iran