Could dropping gluten tame blood sugar and gut woes in diabetes?

NCT ID NCT06900946

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial explores whether a gluten-free diet can ease digestive symptoms and improve blood sugar control in people with type 2 diabetes who have non-celiac gluten sensitivity. Participants first follow a gluten-free diet for six weeks. Those who feel better then take part in a blinded phase where they receive either gluten powder or a placebo (cornstarch) daily, while continuing the diet, to see if symptoms and blood sugar markers change.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gluten-free diet followed by a gluten challenge (gluten powder) versus placebo (cornstarch powder)
What this could lead to
If it works, this could point toward a dietary approach to help manage blood sugar and gut discomfort in people with type 2 diabetes who are sensitive to gluten.
What could go wrong
This is a small, early trial, and results may not apply to everyone. The gluten challenge could trigger symptoms, and the diet is hard to maintain long-term.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Behboud Clinic

    Tehran, 19437, Iran

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