Could common diabetes drugs tame Post-Heart attack inflammation?

NCT ID NCT07295223

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether two diabetes drugs—dapagliflozin and semaglutide—can reduce inflammation after a heart attack. Researchers will enroll 44 people with type 2 diabetes, obesity, and high inflammation levels. Participants will take one of the drugs for 24 weeks, and the study will measure changes in inflammatory markers like hs-CRP and IL-6.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dapagliflozin and semaglutide

What this could lead to

If it works, this could point toward a new way to lower harmful inflammation after a heart attack, potentially reducing long-term complications.

What could go wrong

This is a small pilot study with only 44 participants, so results may not apply widely. Past trials of similar drugs after heart attack did not meet their main goals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ST-elevation myocardial infarction type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital de Especialidades No.1, Centro Médico Nacional del Bajío

    RECRUITING

    León, Guanajuato, 37320, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••