Instituto Mexicano Del Seguro Social

This trial tests whether a two-drug combination (darunavir/cobicistat plus lamivudine) works as well as a standard three-drug combination (darunavir/cobicistat plus tenofovir alafenamide/emtricitabine) in people with HIV whose virus is already suppressed. The study involves 78 ad…

This pilot study tests whether two diabetes drugs—dapagliflozin and semaglutide—can reduce inflammation after a heart attack. Researchers will enroll 44 people with type 2 diabetes, obesity, and high inflammation levels. Participants will take one of the drugs for 24 weeks, and t…

This study tests two diabetes medications (SGLT2 inhibitors and GLP-1 agonists) to see if they can reduce epicardial fat—the fat around the heart—in people who recently had a heart attack. About 136 participants with type 2 diabetes and obesity will have their heart fat measured …

This study tests a dissolvable oral film with a tiny dose of capsaicin (the hot part of chili peppers) in adults who had a stroke within the last 24 hours. The film aims to stimulate nerves in the mouth that may boost blood flow to the brain. 46 participants will receive either t…

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during weight-loss surgery can reduce pain, inflammation, and cell stress afterward. About 104 adults having laparoscopic bariatric surgery will receive either the combo, one drug alone, or…

This study looks at the best dose of a green fluorescent dye (indocyanine green) used during repeat weight-loss surgery to see blood flow. About 108 people with obesity scheduled for this surgery will get different doses of the dye. The goal is to find the smallest dose that stil…