Could a chili pepper film help stroke patients? safety trial begins

NCT ID NCT07406971

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a dissolvable oral film with a tiny dose of capsaicin (the hot part of chili peppers) in adults who had a stroke within the last 24 hours. The film aims to stimulate nerves in the mouth that may boost blood flow to the brain. 46 participants will receive either the capsaicin film or a placebo, and all will get standard stroke care. The main goal is to check for side effects over 72 hours.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
capsaicin oral film
What this could lead to
If safe, this could point toward a new way to improve blood flow to the brain after a stroke, potentially reducing damage.
What could go wrong
This is a small, early-stage safety trial with only 46 people. It is not designed to prove the treatment works, and capsaicin may cause side effects like burning or changes in blood pressure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centenario Hospital Miguel Hidalgo

    RECRUITING

    Aguascalientes, Aguascalientes, 20000, Mexico

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