Could a chili pepper film help stroke patients? safety trial begins
NCT ID NCT07406971
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests a dissolvable oral film with a tiny dose of capsaicin (the hot part of chili peppers) in adults who had a stroke within the last 24 hours. The film aims to stimulate nerves in the mouth that may boost blood flow to the brain. 46 participants will receive either the capsaicin film or a placebo, and all will get standard stroke care. The main goal is to check for side effects over 72 hours.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- capsaicin oral film
- What this could lead to
- If safe, this could point toward a new way to improve blood flow to the brain after a stroke, potentially reducing damage.
- What could go wrong
- This is a small, early-stage safety trial with only 46 people. It is not designed to prove the treatment works, and capsaicin may cause side effects like burning or changes in blood pressure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centenario Hospital Miguel Hidalgo
RECRUITINGAguascalientes, Aguascalientes, 20000, Mexico
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping the brain to restore swallowing after stroke?
- Can Brain-Triggered stimulation reawaken arms after stroke?
- Can lifestyle choices after a stroke extend life and prevent a second one?
- Can Clot-Removing devices improve stroke recovery?
- A tiny neck implant could catch Stroke-Causing clots before they reach the brain
- Can virtual games retrain the brain to restore balance?