Massive GERD study tracks which treatment works best Long-Term

NCT ID NCT00260572

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 2,500 people with gastroesophageal reflux disease (GERD) to compare how well medications and surgery work over time. Researchers will track quality of life, heartburn symptoms, and patient satisfaction. The goal is to identify who benefits most from each treatment and why some treatments fail.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better predict which GERD patients will benefit most from surgery versus medication.

What could go wrong

This is an observational study, not a treatment trial. It will not directly test a new therapy, so results may not change current practice immediately.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dyspepsia gastroesophageal reflux disease Heartburn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UPMC Department of Cardiothoracic Surgery

    Pittsburgh, Pennsylvania, 15213, United States