Knee pain relief without surgery? nerve block injections tested
NCT ID NCT07174167
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether injecting numbing medicine around the knee nerves can reduce pain and improve daily function in people with chronic knee osteoarthritis. 81 adults aged 45–75 received either a local anesthetic alone, a local anesthetic plus steroid, or a sham saline injection. Researchers measured pain levels and walking ability over follow-up visits to see which approach worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
prilocaine and triamcinolone
What this could lead to
If effective, this nerve block could offer a non-surgical option to ease knee pain and improve mobility for people with osteoarthritis.
What could go wrong
This is a small, completed trial (81 people) with short-term follow-up. The effect may be modest or not last long, and results may not apply to everyone with knee OA.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Haydarpasa Numune Training and Research Hospital
Istanbul, Turkey (Türkiye)