Knee surgery recovery: could a common steroid ease pain and get you moving faster?

NCT ID NCT07442812

Recruiting now Symptom relief Sponsor: Haseki Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 270 adults having knee replacement surgery to see if the steroid dexamethasone (given as a pill or through a vein) helps with early recovery. Researchers will measure pain, mobility, nausea, and need for extra painkillers. The study does not assign treatments—patients follow their own surgeon's usual practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone
What this could lead to: If this study shows benefit, it could support using dexamethasone to improve early recovery after knee replacement, reducing pain and nausea.
What could go wrong: This is an observational study, not a randomized trial, so results may be influenced by patient choice of surgeon. The findings may not prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GONARTHROSIS; PRIMARY KNEE OSTEOARTHRITIS TOTAL KNEE ARTHROPLASTY

Contacts and locations

Locations

Sultangazi Haseki Training and Research Hospital
RECRUITING

Istanbul, Istanbul, 34200, Turkey (Türkiye)

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