New procedure offers hope for knee pain without surgery

NCT ID NCT07380906

Recruiting now Symptom relief Sponsor: Joint & Vascular Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 1,200 adults with knee osteoarthritis who have not found relief from standard treatments. They will undergo a procedure called genicular artery embolization, which blocks certain blood vessels to reduce inflammation and pain. Researchers will follow participants for up to 3 years to see if the procedure provides lasting pain relief and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Genicular Artery Embolization (a minimally invasive procedure that blocks blood vessels to reduce knee inflammation and pain)
What this could lead to: If successful, this could provide a new, non-surgical option for long-term knee pain relief in people with osteoarthritis who haven't responded to other treatments.
What could go wrong: This is an observational registry, not a controlled trial, so results may be less definitive. The procedure may not work for everyone, and there are risks like bleeding or infection.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRISTIS

Contacts and locations

Locations

Joint and Vascular Institute
RECRUITING

Libertyville, Illinois, 60048, United States

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