Gene test could predict your salt sensitivity

NCT ID NCT07118592

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how genes influence heart hormones called natriuretic peptides, which help control blood pressure and metabolism. Researchers will give 200 adults with mild high blood pressure low-salt and high-salt diets, plus a saline infusion, to see how their blood pressure and hormone levels change based on their genetic profile. The goal is to understand why some people are more salt-sensitive and to pave the way for personalized treatments for hypertension.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low salt diet, high salt diet, and saline infusion
What this could lead to
If successful, this could lead to personalized dietary recommendations for managing high blood pressure based on a person's genetic makeup.
What could go wrong
This is an early-stage observational study, not a treatment trial. The findings may not directly translate into clinical practice or benefit participants immediately.

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Conditions

The condition(s) this trial relates to.

Genetic Risk Score hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

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