Scientists hunt for genes that protect the lungs

NCT ID NCT00807482

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study aims to find the genes that keep airways healthy and understand how genetic mutations cause primary ciliary dyskinesia (PCD), a rare disease that leads to serious lung problems. Researchers will study people with suspected PCD and healthy family members. The goal is to learn more about how cilia—tiny hair-like structures in the airways—work and how defects in them can lead to common lung diseases like asthma and COPD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could identify key genes involved in lung protection and point toward new treatments for common airway diseases like asthma and COPD.
What could go wrong
This is an observational study, not a treatment trial. It may take years to translate findings into therapies, and the results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

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