Gene therapy trial offers hope for boys with rare immune disease

NCT ID NCT02757911

First seen Apr 21, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This study tested a gene therapy for boys with X-linked chronic granulomatous disease (X-CGD), a rare disorder that leaves them unable to fight off certain infections. The treatment involved taking the patients' own blood stem cells, adding a working copy of the faulty gene, and returning them to the body. The goal was to restore immune function and reduce severe infections and inflammation. Only 3 participants were enrolled before the study was terminated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for X-LINKED CHRONIC GRANULOMATOUS DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Hôpital Necker Enfants Malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.