X-LINKED CHRONIC GRANULOMATOUS DISEASE
Clinical trials for X-LINKED CHRONIC GRANULOMATOUS DISEASE explained in plain language.
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Gene therapy breakthrough offers hope for rare immune disorder
Disease control Recruiting nowThis study tests a new gene therapy called EN-374 for people with X-linked chronic granulomatous disease (X-CGD), a rare immune disorder that causes severe infections. The therapy uses a modified virus to deliver a working gene to fix the immune cells. The trial aims to see if it…
Matched conditions: X-LINKED CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Ensoma • Aim: Disease control
Last updated May 17, 2026 10:06 UTC
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Gene-Editing breakthrough aims to fix immune cells in rare disease
Disease control Recruiting nowThis early-stage trial tests a new gene-editing approach for X-linked chronic granulomatous disease (CGD), a rare immune disorder. Researchers will take stem cells from 10 adult males, fix a specific genetic mutation using base editing, and return the corrected cells after mild c…
Matched conditions: X-LINKED CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 14, 2026 12:06 UTC