X-LINKED CHRONIC GRANULOMATOUS DISEASE
Clinical trials for X-LINKED CHRONIC GRANULOMATOUS DISEASE explained in plain language.
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MRNA therapy gives immune cells a temporary boost against rare infection disease
Disease control Recruiting nowThis early-stage trial tests a new approach for chronic granulomatous disease (CGD), a genetic condition that leaves people vulnerable to severe infections. Researchers take a participant's own white blood cells, use mRNA to correct the genetic defect, and infuse the cells back. …
Matched conditions: X-LINKED CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Gene-Editing breakthrough aims to fix immune cells in rare disease
Disease control Recruiting nowThis early-stage trial tests a new gene-editing approach for X-linked chronic granulomatous disease (X-CGD), a rare immune disorder. Researchers will collect stem cells from 10 adult male participants, use base editing to correct the genetic mutation, and return the cells after m…
Matched conditions: X-LINKED CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Gene therapy aims to fix immune system in rare disease
Disease control Recruiting nowThis study tests a one-time gene therapy called EN-374 for people with X-linked chronic granulomatous disease (X-CGD), a rare immune disorder that causes severe infections. The treatment uses a modified virus to deliver a working gene to blood stem cells, aiming to restore the ab…
Matched conditions: X-LINKED CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Ensoma • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC