Could a booster shot protect newborns from deadly GBS infection?

NCT ID NCT06592586

First seen Jan 31, 2026 · Last updated Jun 08, 2026 · Updated 23 times

Summary

This study follows about 338 healthy pregnant women in Denmark and South Africa who previously received the GBS-NN/NN2 vaccine. Researchers want to see if the immune protection lasts and if a booster dose during a new pregnancy is safe and effective. The goal is to help prevent serious infections like sepsis, pneumonia, and meningitis in newborns.

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Contacts and locations

Locations

  • Aarhus Universitetshospital

    Aarhus N, Central Jutland, 8200, Denmark

  • Hvidovre Hospital - Department Of Obstetrics And Gynaecology

    Copenhagen, Capital Region, 2650, Denmark

  • Sefako Makgatho Health Sciences University, Medunsa Clinical Research Unit (MeCRU)

    Ga-Rankuwa, Gauteng, 0204, South Africa

  • Setshaba Research Centre

    Pretoria, Guateng Province, 0152, South Africa

  • Sygehus Lillebælt - Kolding Sygehus

    Kolding, Region Syddanmark, 6000, Denmark

  • Wits Reproductive Health and HIV Institute (Wits RHI)

    Johannesburg, Guateng Province, 2001, South Africa

Conditions

Explore the condition pages connected to this study.