Can a simple test guide chemo for pancreatic cancer patients?

NCT ID NCT04472910

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a biomarker called GATA6 can help predict how well patients with resectable pancreatic cancer respond to chemotherapy before and after surgery. About 84 participants will provide tumor samples to measure GATA6 levels, then receive a standard chemo regimen. The goal is to see if GATA6 levels are linked to longer disease-free survival, which could lead to more personalized treatment choices in the future.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma malignant pancreatic neoplasm pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BC Cancer Agency Vancouver

    Vancouver, British Columbia, Canada

  • Jewish General Hospital

    Montreal, Quebec, Canada

  • Kingston Health Sciences Centre

    Kingston, Ontario, Canada

  • London Health Sciences Centre

    London, Ontario, Canada

  • Ottawa Hospital

    Ottawa, Ontario, Canada

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2N9, Canada

  • Sunnybrook Hospital/Odette Cancer Centre

    Toronto, Ontario, Canada

  • Unity Health (St. Joseph's and St. Michael's)

    Toronto, Ontario, Canada