New trick before surgery may prevent deadly leaks in esophageal cancer patients

NCT ID NCT07449208

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a procedure called gastric preconditioning—done before esophageal cancer surgery—can lower the risk of a serious complication called an anastomotic leak. The procedure uses a tiny tube to redirect blood flow in the stomach, which may help the surgical connection heal better. The study will include 40 high-risk patients and track how many develop leaks after their main surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous angioembolization (a procedure to redirect blood flow in the stomach before surgery)

What this could lead to

If successful, this approach could reduce the risk of serious post-surgery complications (anastomotic leaks) in patients undergoing esophageal cancer removal.

What could go wrong

This is a small early-phase study with only 40 participants, so results may not apply to all patients. The procedure itself carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak esophageal cancer neoplasm of esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All protocol activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••