Glowing dye during surgery may cut dangerous bowel leaks
NCT ID NCT06793280
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether injecting a special dye (ICG) during laparoscopic colorectal cancer surgery helps surgeons see blood flow and choose a safer spot to cut. Over 560 adults took part, with half getting the dye and half relying on the surgeon's usual judgment. The main goal was to see if the dye reduces the rate of anastomotic leaks, a serious complication that can cause severe illness or death.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
indocyanine green (ICG) dye injection
What this could lead to
If this method works, it could help surgeons decide where to cut during colorectal surgery, potentially lowering the risk of dangerous post-surgery leaks.
What could go wrong
An earlier small trial found no clear benefit, so this larger study may also show no significant reduction in leaks. The dye itself can cause rare allergic reactions.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Lidia Castagneto Gissey
Roma, Italy, 00161, Italy