Can a seizure drug tame autism irritability? new trial aims to find out
NCT ID NCT07635862
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether ganaxolone, a drug already approved for certain seizures, can reduce irritability in autistic children aged 5 to 17. About 66 participants will receive either the drug or a placebo for 12 weeks. The main goal is to see if it improves emotional regulation and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ganaxolone (Ztalmy)
- What this could lead to
- If it works, this could offer a new option to reduce irritability and repetitive behaviors in autistic children, improving daily life.
- What could go wrong
- This is an early phase 2 trial with only 66 participants, so results may not apply widely. The drug may cause side effects or show no benefit over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AUTISM IN CHILDREN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Stanford University
Stanford, California, 94305, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Light-Up training pods may sharpen reflexes in autistic teen athletes
- Could online coaching for parents boost autistic Children's social skills?
- Can a new curriculum help autistic adults navigate romance?
- Could a phone app help parents of kids with special needs thrive?
- Can a parent support group help teens with both autism and anorexia?
- Could a Self-Help guide transform parenting stress for families of kids with NDD?