Hand therapy plus gabapentin may ease carpal tunnel pain better than pills alone

NCT ID NCT06778798

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding a specific hand and arm therapy technique (called median nerve neural mobilization) to the pain medication gabapentin could reduce pain more than gabapentin alone in people with carpal tunnel syndrome. 72 adults with confirmed carpal tunnel syndrome took part. The main goal was to measure pain changes using a simple pain scale, and the study also checked how well the hand and arm functioned.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gabapentin (oral capsules) and median nerve neural mobilization (manual therapy)

What this could lead to

If it works, this could point toward a more effective, non-surgical way to manage carpal tunnel pain by combining medication with physical therapy.

What could go wrong

This is a small, completed Phase 4 trial with only 72 participants, so results may not apply to everyone. The manual therapy technique requires a skilled practitioner, and gabapentin can cause side effects like dizziness or drowsiness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ciudad Hospitalaria Enrique Tejera

    Valencia, Carabobo, 02001, Venezuela