Eye injection shows promise against fungal ulcers

NCT ID NCT02731638

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding an injection of the antifungal drug voriconazole into the eye could improve treatment for fungal corneal ulcers. 70 people with moderate to severe infections received either standard antifungal drops alone or drops plus three injections over 10 days. The goal was to see if the injection helped clear the fungus faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

voriconazole injection plus natamycin drops

What this could lead to

If successful, this approach could become a standard treatment for fungal eye infections, reducing the need for more invasive procedures.

What could go wrong

This is a single, completed trial with 70 participants. The results may not apply to all types of fungal infections or to patients with more severe disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

corneal disorder corneal ulcer fungal keratitis keratitis ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aravind Eye Hospitals

    Pondicherry, Tamil Nadu, India

  • Francis I. Proctor Foundation at UCSF

    San Francisco, California, 94143, United States