Can Lab-Grown tumors stop breast cancer from coming back?
NCT ID NCT05464082
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new approach called Functional Precision Oncology for people with triple-negative or HR-low/HER2- breast cancer at high risk of early recurrence. Researchers will create personalized tumor models (in mice and lab dishes) from each patient's cancer to find the most effective treatments. The goal is to see if this method can predict and prevent the cancer from returning early. The study involves 80 participants and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Functional Precision Oncology (tumor models including patient-derived xenografts and organoids)
- What this could lead to
- If successful, this approach could help doctors identify the most effective treatments for each patient's unique tumor, potentially reducing the risk of early cancer return.
- What could go wrong
- This is a small, early-phase study (80 participants) focused on feasibility, not a proven treatment. The tumor models may not always predict real patient responses, and the approach may not improve outcomes for everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Huntsman Cancer Institute at University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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