New clot-busting shot could save lives in dangerous lung condition

NCT ID NCT06362746

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of a clot-dissolving drug (staphylokinase) in 486 adults with intermediate high-risk pulmonary embolism—a serious blood clot in the lungs. The goal is to see if it prevents death, heart collapse, or another clot compared to a placebo. Participants must have a confirmed clot and signs of heart strain but stable blood pressure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asinovskaya District Hospital

    COMPLETED

    Asino, Tomsk Oblast, 636840, Russia

  • Belgorod Regional Clinical Hospital of St. Joseph

    RECRUITING

    Belgorod, 308007, Russia

    Contact Email: •••••@•••••

    Contact

  • Center of Neurology and Cardiology

    RECRUITING

    Kirov, 610035, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City Clinical Hospital of Emergency medicine №25

    RECRUITING

    Volgograd, 400138, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City Clinical Hospital №4

    WITHDRAWN

    Perm, 614107, Russia

  • City Hospital No. 15

    RECRUITING

    Saint Petersburg, 198205, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City Hospital No. 26

    RECRUITING

    Saint Petersburg, 196247, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • F.I. Inozemtsev City Clinical Hospital

    RECRUITING

    Moscow, 105187, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • G.A. Zakharyin Clinical hospital №6

    RECRUITING

    Penza, 440071, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kuzbass Cardiology center

    RECRUITING

    Kemerovo, 650002, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lipetsk City Hospital No. 4 "Lipetsk-Med"

    RECRUITING

    Lipetsk, 398006, Russia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Moscow Multidisciplinary Clinical Center "Kommunarka"

    RECRUITING

    Moscow, 108814, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • N.A. Semashko Nizhny Novgorod Regional Clinical Hospital

    RECRUITING

    Nizhny Novgorod, 603093, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • N.N. Burdenko Penza Regional Clinical hospital

    WITHDRAWN

    Penza, 440026, Russia

  • RZD Medicine hospital

    RECRUITING

    Barnaul, Altayskiy Kray, 656038, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Regional Clinical Hospital №2

    RECRUITING

    Krasnodar, 350012, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • S.P. Botkin City Clinical Hospital

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • S.S. Yudin City Clinical Hospital

    RECRUITING

    Moscow, 115446, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tomsk regional cilinical hospital

    RECRUITING

    Tomsk, 634063, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tver Regional Clinical Hospital

    RECRUITING

    Tver', 170036, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ufa Emergency City Hospital

    RECRUITING

    Ufa, 450092, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • V.F. Dolgopolov Vyselki Central District Hospital

    RECRUITING

    Vyselki, Krasnodarskiy Kray, 353100, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • V.M. Buyanov City Clinical Hospital

    RECRUITING

    Moscow, 115516, Russia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • V.P. Polyakov Samara Regional Clinical Cardiology Dispensary

    RECRUITING

    Samara, 443070, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact