Sound waves take on pancreatic cancer: new trial tests focused ultrasound
NCT ID NCT07325214
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This clinical trial tests whether adding focused ultrasound (IMD10) to standard chemotherapy can help people with borderline resectable or locally advanced pancreatic cancer. The study will enroll 136 adults aged 18-85 with confirmed pancreatic ductal adenocarcinoma. Half will get chemotherapy alone, the other half chemotherapy plus focused ultrasound, and researchers will track overall survival to see if the combination works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- focused ultrasound (IMD10 device) plus chemotherapy (irinotecan, oxaliplatin, 5-FU, leucovorin)
- What this could lead to
- If it works, this could offer a new way to shrink pancreatic tumors, potentially making more patients eligible for surgery and improving survival.
- What could go wrong
- This is a relatively small, early-stage trial (136 people) and focused ultrasound for pancreatic cancer is still experimental. It may not improve outcomes or could have unexpected side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Seoul National University Bundang Hospital,
Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
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University of Virginia Medical Center
Charlottesville, Virginia, 22908, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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