Sound waves take on pancreatic cancer: new trial tests focused ultrasound

NCT ID NCT07325214

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This clinical trial tests whether adding focused ultrasound (IMD10) to standard chemotherapy can help people with borderline resectable or locally advanced pancreatic cancer. The study will enroll 136 adults aged 18-85 with confirmed pancreatic ductal adenocarcinoma. Half will get chemotherapy alone, the other half chemotherapy plus focused ultrasound, and researchers will track overall survival to see if the combination works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

focused ultrasound (IMD10 device) plus chemotherapy (irinotecan, oxaliplatin, 5-FU, leucovorin)

What this could lead to

If it works, this could offer a new way to shrink pancreatic tumors, potentially making more patients eligible for surgery and improving survival.

What could go wrong

This is a relatively small, early-stage trial (136 people) and focused ultrasound for pancreatic cancer is still experimental. It may not improve outcomes or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

    Contact

  • Seoul National University Bundang Hospital,

    Gyeonggi-do, 13620, South Korea

    Contact

  • Seoul National University Hospital

    Seoul, 03080, South Korea

    Contact

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

    Contact

  • University of Virginia Medical Center

    Charlottesville, Virginia, 22908, United States

    Contact