New registry aims to personalize blood thinners after TAVR

NCT ID NCT06000943

Recruiting now Knowledge-focused Sponsor: Niguarda Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 2500 people who had a TAVR procedure to replace a narrowed heart valve. Researchers will track bleeding and clotting events over time to see how different blood-thinner medicines affect risk. The goal is to find the best treatment plan for each patient based on their surgical risk level.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors choose the safest blood-thinner plan for each patient after TAVR, reducing heart attacks, strokes, and bleeding.
What could go wrong: This is an observational registry, not a treatment test. It can show patterns but cannot prove which therapy is best. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC VALVE STENOSIS TRANSCATHETER AORTIC VALVE REPLACEMENT

Contacts and locations

Locations

A.O.U. Città della Salute e della Scienza di Torino
RECRUITING

Torino, Italy
ASST GOM Niguarda
RECRUITING

Milan, Italia, 20162, Italy
Azienda Ospedaliera Sant'Andrea
RECRUITING

Roma, Italy
Cardiocenter, 3rd Medical School, Charles University and University Hospital Kralovske Vinohrady
RECRUITING

Prague, 10034, Czechia
Complejo Asistencial Dr. Sótero del Río
RECRUITING

Santiago, Chile
Humanitas Research Hospital
RECRUITING

Rozzano, Milano, 20089, Italy
IRCCS Ospedale Policlinico San Martino
RECRUITING

Genova, Italy
IRCCS Policlinico San Donato
RECRUITING

San Donato Milanese, Milano, Italy
OLV Hospital
RECRUITING

Aalst, Belgium
Ospedale Galeazzi Sant'Ambrogio
RECRUITING

Milan, Italy
Puerto Real University Hospital, Puerto Real
RECRUITING

Cadiz, Spain
San Carlo Hospital
RECRUITING

Potenza, Italy

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