Sound waves vs. prostate cancer: new trial aims to zap tumors without surgery

NCT ID NCT05438563

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This Mayo Clinic trial is testing a procedure called MRI-guided TULSA for men with low to intermediate grade prostate cancer. It uses high-energy sound waves guided by MRI to precisely destroy tumor cells, aiming to avoid surgery or radiation. The study will enroll 100 men aged 45-80 and track how well the treatment controls cancer while preserving urinary and sexual function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI-guided transurethral ultrasound ablation (TULSA)

What this could lead to

If successful, this could offer a minimally invasive alternative to surgery or radiation for certain prostate cancers, potentially preserving quality of life.

What could go wrong

This is an early-stage trial with only 100 participants. It may not work for all patients, and risks include treatment failure, side effects, or need for additional therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact