Poop pills could tame tough IBS – early trial underway
NCT ID NCT07481422
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether capsules containing freeze-dried fecal matter from healthy donors can safely reduce symptoms in adults with irritable bowel syndrome (IBS) that hasn't responded to usual treatments. 70 participants will be randomly assigned to receive either the fecal transplant capsules or placebo for three days. Researchers will track symptom severity, quality of life, and side effects over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
freeze-dried fecal microbiota (from healthy donors) in capsules
What this could lead to
If it works, this could offer a new, non-drug option for people with stubborn IBS that hasn't improved with standard treatments.
What could go wrong
This is an early phase 1/2 trial with only 70 people, so results may not apply to everyone. The treatment involves swallowing donor stool material, which carries unknown long-term risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clinical Hospital Center Rijeka
RECRUITINGRijeka, 51000, Croatia
Contact Phone: •••-•••-•••• Email: •••••@•••••