Brain scans reveal how mindfulness and therapy calm Kids' tummy troubles

NCT ID NCT03518216

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how a behavioral treatment called ADAPT affects brain activity in children aged 11–16 with functional abdominal pain and anxiety. The treatment combines mindfulness meditation and cognitive behavioral therapy over six sessions, delivered remotely. Researchers used fMRI scans to see changes in brain connections related to pain and emotion. The goal was to understand how the treatment works in the brain, not to test if it cures the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ADAPT (Aim to Decrease Anxiety and Pain Treatment) – a remotely delivered behavioral intervention combining mindfulness meditation and cognitive behavioral therapy

What this could lead to

If successful, this could help design more targeted non-drug treatments for children with functional abdominal pain and anxiety.

What could go wrong

This is a small, early-stage study (49 participants) focused on understanding brain changes, not on proving the treatment works. Results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANXIETY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Michigan State University

    Grand Rapids, Michigan, 49503, United States