Less fluid during surgery may lead to better recovery
NCT ID NCT01424150
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether giving less fluid during major abdominal surgery helps patients recover better than giving more fluid. Over 3,000 adults having elective abdominal surgery were randomly assigned to either a restrictive (less than 2 liters per day) or liberal (about 6 liters per day) fluid plan. The main goal was to see which group had better disability-free survival up to one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intravenous fluids (restrictive vs liberal protocol)
What this could lead to
If successful, this could establish a standard for how much fluid to give during major abdominal surgery, potentially reducing complications and improving recovery.
What could go wrong
This is a completed trial, so results are already known. However, the optimal fluid strategy may still depend on individual patient factors and surgical context, limiting broad applicability.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Alfred Hospital
Melbourne, Victoria, 3004, Australia