Could a simple stool test replace colonoscopy for cancer surveillance?

NCT ID NCT06983639

Recruiting now Diagnosis Sponsor: Sorlandet Hospital HF Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to monitor people who have had polyps removed from their colon: a fecal test that checks for blood in stool versus a standard colonoscopy. Researchers want to see if the simpler stool test is just as good at catching new cancers or high-risk polyps. About 4,000 participants will be followed over time to compare cancer rates and deaths between the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fecal occult blood test (FIT) and colonoscopy
What this could lead to: If successful, this could show that a simple stool test is as effective as colonoscopy for follow-up, reducing the need for invasive procedures.
What could go wrong: This is a large but early-stage comparison; the stool test may miss some cancers or polyps that colonoscopy would find, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL ADENOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal neoplasm polyp

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL NEOPLASMS

Contacts and locations

Locations

Sørlandet sykehus HF
RECRUITING

Arendal, Agder, 4838, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.