Could a simple stool test replace colonoscopy for cancer surveillance?

NCT ID NCT06983639

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways to monitor people who have had polyps removed from their colon: a fecal test that checks for blood in stool versus a standard colonoscopy. Researchers want to see if the simpler stool test is just as good at catching new cancers or high-risk polyps. About 4,000 participants will be followed over time to compare cancer rates and deaths between the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal occult blood test (FIT) and colonoscopy

What this could lead to

If successful, this could show that a simple stool test is as effective as colonoscopy for follow-up, reducing the need for invasive procedures.

What could go wrong

This is a large but early-stage comparison; the stool test may miss some cancers or polyps that colonoscopy would find, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal neoplasm polyp

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sørlandet sykehus HF

    RECRUITING

    Arendal, Agder, 4838, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••