New drug aims to protect transplanted kidneys

NCT ID NCT06059664

First seen Apr 15, 2026 · Last updated Jun 19, 2026 · Updated 12 times

Summary

This study tests whether finerenone, a drug already used for kidney disease, can help protect transplanted kidneys. About 100 adults who received a kidney transplant 1 to 10 years ago will take either finerenone or a placebo daily for 12 months. Researchers will check how well the drug is tolerated and whether it improves kidney health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UNC Eastowne Kidney Transplant Clinic

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Finerenone (Kerendia) oral tablet

What this could lead to

If successful, finerenone could become a new option to protect kidney function and reduce damage in transplant recipients, potentially delaying graft failure.

What could go wrong

This is an early Phase 2 trial with only 100 participants, so results may not apply broadly. Finerenone can raise potassium levels, requiring careful monitoring and dose adjustments.

Conditions

The condition(s) this trial relates to.

Albuminuria heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.