New pill could cut heart failure deaths when given early in hospital
NCT ID NCT07397650
First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This study tests whether starting the drug finerenone early during a hospital stay for acute heart failure can improve outcomes. About 550 adults with heart failure and preserved ejection fraction will receive either finerenone or a placebo. Researchers will track deaths, worsening heart failure, and symptom changes over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Finerenone oral tablet
- What this could lead to
- If successful, this could show that starting finerenone early in the hospital reduces death and worsening heart failure events after discharge.
- What could go wrong
- This is a phase 4 trial, but heart failure is complex and results may not apply to all patients. The benefit may be modest or not statistically significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chita Peninsula General Medical Center
RECRUITINGHanda, Aichi-ken, Japan
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Chutoen General Medical Center
RECRUITINGKakegawa, Shizuoka, Japan
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Ehime University Hospital
RECRUITINGTōon, Ehime, Japan
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Gunma Prefectural Cardiovascular Center
NOT_YET_RECRUITINGMaebashi, Gunma, Japan
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Gunma University Hospital
RECRUITINGMaebashi, Gunma, Japan
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Hokkaido Cardiovascular Hospital
RECRUITINGSapporo, Hokkaido, Japan
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Iizuka Hospital
RECRUITINGIizuka, Fukuoka, Japan
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Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital
NOT_YET_RECRUITINGNagoya, Aichi-ken, Japan
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Japanese Red Cross Fukuoka Hospital
NOT_YET_RECRUITINGFukuoka, Fukuoka, Japan
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Juntendo University Hospital
RECRUITINGTokyo, Japan
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Juntendo University Shizuoka Hospital
NOT_YET_RECRUITINGIzunokuni, Shizuoka, Japan
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Kindai University Hospital
RECRUITINGSakai, Osaka, Japan
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Kitasato University Hospital
NOT_YET_RECRUITINGSagamihara, Kanagawa, Japan
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NHO Takasaki General Medical Center
RECRUITINGTakasaki, Gunma, Japan
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Nagoya University Hospital
RECRUITINGNagoya, Aichi-ken, Japan
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National Center for Geriatrics and Gerontology
NOT_YET_RECRUITINGŌbu, Aichi-ken, Japan
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National Cerebral and Cardiovascular Center
NOT_YET_RECRUITINGSuita, Osaka, Japan
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Osaka General Medical Center
RECRUITINGOsaka, Japan
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Saitama Medical Center
NOT_YET_RECRUITINGKawagoe, Saitama, Japan
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The University of Osaka Hospital
RECRUITINGSuita, Osaka, Japan
-
Toyota Kosei Hospital
RECRUITINGToyota, Aichi-ken, Japan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a second diuretic boost recovery from heart failure?
- 21-Protein blood test aims to spot hidden heart failure in the ER
- Hospital heart pill may prevent repeat crises
- Heart failure fluid study: which furosemide method works best?
- Can MRI predict heart failure outcomes? new study investigates
- Heart failure emergency: which drug works best first?