New pill could cut heart failure deaths when given early in hospital
NCT ID NCT07397650
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether starting the drug finerenone early during a hospital stay for acute heart failure can improve outcomes. About 550 adults with heart failure and preserved ejection fraction will receive either finerenone or a placebo. Researchers will track deaths, worsening heart failure, and symptom changes over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Finerenone oral tablet
What this could lead to
If successful, this could show that starting finerenone early in the hospital reduces death and worsening heart failure events after discharge.
What could go wrong
This is a phase 4 trial, but heart failure is complex and results may not apply to all patients. The benefit may be modest or not statistically significant.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chita Peninsula General Medical Center
RECRUITINGHanda, Aichi-ken, Japan
Contact
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Chutoen General Medical Center
RECRUITINGKakegawa, Shizuoka, Japan
Contact
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Ehime University Hospital
RECRUITINGTōon, Ehime, Japan
Contact
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Gunma Prefectural Cardiovascular Center
NOT_YET_RECRUITINGMaebashi, Gunma, Japan
Contact
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Gunma University Hospital
RECRUITINGMaebashi, Gunma, Japan
Contact
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Hokkaido Cardiovascular Hospital
RECRUITINGSapporo, Hokkaido, Japan
Contact
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Iizuka Hospital
RECRUITINGIizuka, Fukuoka, Japan
Contact
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Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital
NOT_YET_RECRUITINGNagoya, Aichi-ken, Japan
Contact
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Japanese Red Cross Fukuoka Hospital
NOT_YET_RECRUITINGFukuoka, Fukuoka, Japan
Contact
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Juntendo University Hospital
RECRUITINGTokyo, Japan
Contact
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Juntendo University Shizuoka Hospital
NOT_YET_RECRUITINGIzunokuni, Shizuoka, Japan
Contact
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Kindai University Hospital
RECRUITINGSakai, Osaka, Japan
Contact
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Kitasato University Hospital
NOT_YET_RECRUITINGSagamihara, Kanagawa, Japan
Contact
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NHO Takasaki General Medical Center
RECRUITINGTakasaki, Gunma, Japan
Contact
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Nagoya University Hospital
RECRUITINGNagoya, Aichi-ken, Japan
Contact
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National Center for Geriatrics and Gerontology
NOT_YET_RECRUITINGŌbu, Aichi-ken, Japan
Contact
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National Cerebral and Cardiovascular Center
NOT_YET_RECRUITINGSuita, Osaka, Japan
Contact
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Osaka General Medical Center
RECRUITINGOsaka, Japan
Contact
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Saitama Medical Center
NOT_YET_RECRUITINGKawagoe, Saitama, Japan
Contact
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The University of Osaka Hospital
RECRUITINGSuita, Osaka, Japan
Contact
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Toyota Kosei Hospital
RECRUITINGToyota, Aichi-ken, Japan
Contact