Skin cells may reveal secrets of deadly aortic bulges

NCT ID NCT06786754

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at skin cells (fibroblasts) from people with Marfan syndrome and other genetic conditions that cause thoracic aortic aneurysms (a bulging of the main artery in the chest). Researchers want to find out how these cells behave differently and what genes or proteins are involved, which could lead to better ways to predict or treat the disease. The study involves 15 adults and does not test any new treatment.

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Conditions

The condition(s) this trial relates to.

Marfan syndrome Rare Diseases thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiovascular Genetic Centre IRCCS Policlinico San Donato

    San Donato Milanese, Milan, 20097, Italy