Fiber fix? study tests if a simple supplement boosts arthritis Drug's power

NCT ID NCT05812157

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding a daily fiber supplement (inulin) to standard anti-IL-17 therapy could improve gut bacteria balance and treatment response in 76 adults with axial spondyloarthritis. Participants took either fiber or a placebo powder for three months. The main goal was to see if fiber increased beneficial gut bacteria. If successful, this simple addition might help patients get more out of their medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

inulin (Fibruline) fiber supplement

What this could lead to

If it works, this could point toward a simple dietary addition that helps people with axial spondyloarthritis respond better to their anti-IL-17 medication.

What could go wrong

This is a small, early-stage study focused on gut bacteria changes, not direct symptom improvement. The fiber supplement may not meaningfully affect disease activity or treatment outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AXIAL SPONDYLOARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Axial Spondyloarthritis Dysbiosis spondyloarthropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Montpellier University Hospital

    Montpellier, Hérault, 34000, France

  • Nîmes University Hospital

    Nîmes, Gard, 30029, France

  • Tours Regional University Hospital (Bretonneau)

    Tours, Indre-et-Loire, 37032, France