Umbilical cord patch used in womb to repair spina bifida
NCT ID NCT04243889
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new way to repair spina bifida before birth using a tiny camera and a patch made from donated human umbilical cord tissue. The patch is placed over the spinal cord to create a watertight seal, which may reduce problems after birth. The trial includes 50 pregnant women carrying a baby with spina bifida, and the surgery is done between 22 and 25 weeks of pregnancy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryopreserved human umbilical cord allograft (NEOX Cord 1K)
What this could lead to
If successful, this could offer a less invasive way to repair spina bifida before birth, potentially reducing the need for postnatal surgeries and improving outcomes.
What could go wrong
This is an early-stage trial with only 50 participants, so results may not apply to everyone. The procedure is complex and carries risks for both mother and fetus, including preterm birth or failed repair.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States