Fetal stem cells aim to mend broken bones in infants
NCT ID NCT03706482
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase trial tests whether fetal stem cells given before or after birth can safely help infants with severe osteogenesis imperfecta, a genetic condition causing fragile bones and frequent fractures. Up to 18 children will receive multiple doses of the cells. The main goal is to check safety, but researchers will also track fracture rates and bone density.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fetal liver-derived mesenchymal stem cells (BOOST cells)
What this could lead to
If it works, this could point toward a treatment that reduces fractures and improves bone strength in children with severe brittle bone disease.
What could go wrong
This is a very early, small trial (18 participants) focused mainly on safety. The cells may cause immune reactions or fail to improve bone health, and long-term effects are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Karolinska University Hospital
Stockholm, Stockholm County, 171 76, Sweden