Cure My Disease

Don't miss your cure!

 Log in / Sign up

New drug combo aims to boost IVF success for women with hormone deficiency

NCT ID NCT07340827

Recruiting now Disease control Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This Phase 3 trial tests a new combination of two hormones (follitropin alfa and lutropin alfa) against a standard treatment (hMG) for Japanese women with LH and FSH deficiency who are undergoing IVF. The goal is to see which treatment helps produce more eggs for retrieval. About 266 women will participate, and the study lasts up to 13 months for those who become pregnant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
follitropin alfa and lutropin alfa (a combination of two hormones to stimulate egg growth)
What this could lead to
If this works, it could offer a more effective fertility treatment option for Japanese women with hormone deficiencies who need IVF.
What could go wrong
This is a Phase 3 trial, but it is still experimental. The new drug may not work better than the existing treatment, and side effects like ovarian hyperstimulation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FOLLICLE STIMULATING HORMONE DEFICIENCY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hypogonadotropic hypogonadism hypogonadotropic hypogonadism 24 without anosmia infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILITY

Contacts and locations

Locations

  • Akita University Hospital - Dept of Obstetrics/Gynecology

    RECRUITING

    Akita, Akita, 010-8543, Japan

  • Dokkyo Medical University Hospital - Dept of Reproduction Center

    RECRUITING

    Shimotsuga-gun, Tochigi, 321-0293, Japan

  • Hanabusa Women's Clinic Hanabusa Women's Central Fertility Clinic - Dept of Obstetrics/Gynecology

    RECRUITING

    Kobe, Hyōgo, 650-0021, Japan

  • Haruki Ladies Clinic - Dept of Gynecology

    RECRUITING

    Osaka, Osaka, 542-0081, Japan

  • JA-Nagano Shinonoi General Hospital - Dept of Obstetrics/Gynecology

    RECRUITING

    Nagano, Nagano, 388-8004, Japan

  • Juntendo University Hospital - Dept of Obstetrics/ Gynecology

    RECRUITING

    Bunkyō City, Tokyo-To, 113-8431, Japan

  • KASHIWAZAKI OB/GYN CLINIC - Dept of Obstetrics/Gynecology

    RECRUITING

    Saitama-shi, Saitama, 330-0855, Japan

  • Kameda IVF Clinic Makuhari - Dept of Obstetrics/Gynecology

    RECRUITING

    Chiba, Chiba, 261-8501, Japan

  • Kamiya Ladies Clinic - Dept of Gynecology

    RECRUITING

    Sapporo, Hokkaido, 060-0003, Japan

  • Ladies Clinic Cosmos - Dept of Infertility Treatment

    RECRUITING

    Kochi, Kochi, 780-0072, Japan

  • Nagano Municipal Hospital - Dept of Gynecology

    RECRUITING

    Nagano, Nagano, 381-8551, Japan

  • Omiya Ladies Clinic - Dept of Gynecology

    RECRUITING

    Saitama-shi, Saitama, 330-8669, Japan

  • Sankeikai IVF Osaka Clinic - Dept of Obstetrics/Gynecology

    RECRUITING

    Higashiosaka-shi, Osaka, 577-0012, Japan

  • Sophia Ladies Clinic - Dept of Obstetrics/Gynecology

    RECRUITING

    Sagamihara-shi, Kanagawa, 252-0233, Japan

  • Sora no Mori Clinic - Dept of Obstetrics/Gynecology

    RECRUITING

    Shimajiri-gun, Okinawa, 901-0406, Japan

  • Sugiyama Clinic Marunouchi - Dept of Obstetrics/ Gynecology

    RECRUITING

    Chiyoda-ku, Tokyo-To, 100-0005, Japan

  • Sugiyama Clinic Shinjuku - Dept of Reproductive Medical

    RECRUITING

    Shinjuku-ku, Tokyo-To, 160-0023, Japan

  • Toho University Omori Medical Center - Dept of Obstetrics/Gynecology

    RECRUITING

    Ōta-ku, Tokyo-To, 143-8541, Japan

  • Tokushima University Hospital - Dept of Obstetrics/Gynecology

    RECRUITING

    Tokushima, Tokushima, 770-8503, Japan

  • University of Tokyo Hospital - Dept of Obstetrics

    RECRUITING

    Bunkyō City, Tokyo-To, 113-8655, Japan

  • YOKOTA Maternity Hospital - Dept of Reproductive Medical Gynecology

    RECRUITING

    Maebashi, Gunma, 371-0031, Japan

More trials for these conditions

Other studies related to the condition(s) this trial covers.