New combo therapy aims to cut stomach bleeding risk in heart patients
NCT ID NCT07497893
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether adding fexuprazan, a stomach acid reducer, to standard blood thinners can prevent upper gastrointestinal bleeding in people with atrial fibrillation. About 1,000 high-risk participants will be randomly assigned to receive either the combination therapy or blood thinners alone. The main goal is to see if fexuprazan reduces the chance of serious stomach bleeding over one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fexuprazan
- What this could lead to
- If it works, this could show that adding fexuprazan to blood thinners reduces the risk of serious stomach bleeding in people with atrial fibrillation.
- What could go wrong
- This trial hasn't started yet, and it's testing a new use for fexuprazan. The expected benefit is based on assumptions, and the results may not show a clear advantage over current care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ewha Womans University Mokdong Hospital
Seoul, 1071, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Wrist-Worn sensor outsmart atrial fibrillation?