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Can a simple leg test pinpoint which nerve is compressed?

NCT ID NCT07799142

Diagnosis Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 09, 2026 · Updated 2 times

Summary

This study at Marmara University examines how well the femoral stretch test, a physical exam maneuver, detects compression of the L2, L3, or L4 nerve roots in people with lumbar radiculopathy. Researchers will include 120 patients with MRI-confirmed single-root compression who are scheduled for a routine steroid injection. Before and after the injection, they will record test results and pain levels to see if the test's accuracy differs by nerve root and if the injection changes test outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Femoral stretch test (a physical examination maneuver) and transforaminal epidural steroid injection (a standard procedure given as part of routine care, not as the study intervention)
What this could lead to
If the femoral stretch test proves reliable for L2, L3, or L4 nerve root compression, doctors could use it to better pinpoint the affected nerve root without relying solely on imaging, potentially speeding up diagnosis and treatment planning.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The test's accuracy may vary by nerve root, and results from this single-center study may not apply to all patients with lumbar radiculopathy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with lumbar radicular pain who are evaluated at a tertiary pain medicine clinic and are scheduled to undergo clinically indicated single-level, unilateral transforaminal epidural steroid injection targeting the L2, L3, or L4 nerve root will be prospectively enrolled.

Ages

18 months and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a diagnosis of lumbar radicular pain based on medical history, physical examination, and imaging findings. * Patients with unilateral L2, L3, or L4 nerve root involvement who are scheduled to undergo single-level, unilateral transforaminal epidural steroid injection targeting the corresponding nerve root. Exclusion Criteria: * Presence of diabetes mellitus or other medical conditions that may cause polyneuropathy. * Presence of active radicular pain originating from lumbosacral nerve roots other than L2, L3, or L4. * Unavailability of relevant radiological imaging. * Cognitive impairment that may interfere with clinical assessment. * Pregnancy. * Presence of local or systemic infection.

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Conditions

The condition(s) this trial relates to.

radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lumbar radiculopathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Marmara University Pendik Training and Research Hospital

    Istanbul, Pendik, 34899, Turkey (Türkiye)

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