Nerve gliding or back manipulation: which eases knee pain better?
NCT ID NCT07712146
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study tests whether adding femoral nerve gliding or lumbopelvic manipulation to standard hip-knee exercises improves pain, knee function, and nerve health in people with patellofemoral pain syndrome (front knee pain). Sixty adults aged 18–35 with unilateral knee pain will be randomly assigned to one of three groups: exercises alone, exercises plus nerve gliding, or exercises plus back manipulation. All treatments last 6 weeks, and outcomes are measured before and after.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- femoral nerve gliding technique and lumbopelvic manipulation
- What this could lead to
- If effective, these techniques could offer better pain relief and knee function for people with patellofemoral pain syndrome, potentially reducing the need for more invasive treatments.
- What could go wrong
- This is a small, early-stage study with only 60 participants, so results may not apply to everyone. The techniques are manual therapies, and their effectiveness may vary between individuals.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of physical therapy-Cairo University
Cairo, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
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